VigiPallia : Résultats

CURROW, David

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Clinically significant depressive symptoms are prevalent in people with extremely short prognoses - a systematic review

LEE, Wei ; PULBROOK, Marley ; SHEEHAN, Caitlin ; KOCHOVSKA, Slavica ; CHANG, Sungwon ; HOSIE, Annmarie ; LOBB, Elizabeth ; PARKER, Deborah ; DRAPER, Brian ; AGAR, Meera R. ; CURROW, David
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 17/07/2020, p. -

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Covid-19: guidance on palliative care from a european respiratory society international task force

JANSSEN, Daisy J. A. ; EKSTROM, Magnus ; CURROW, David ; JOHNSON, Miriam J. ; MADDOCKS, Mathew ; SIMONDS, Anita K. ; TONIA, Thomy ; MARSAA, Kristoffer
The European respiratory journal, 16/07/2020, p. -

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What are the factors identifying caregivers who need help in managing medications for palliative care patients at home? - a population survey

TAIT, Paul ; CUTHBERTSON, Elizabeth ; CURROW, David
JOURNAL OF PALLIATIVE MEDICINE, 10/03/2020, Pagination inconnue

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A randomised, double-blind, crossover, dose ranging study to determine the optimal dose of oral opioid to treat breakthrough pain for patients with advanced cancer already established on regular opioids

CURROW, David ; CLARK, K. ; LOUW, S. ; FAZEKAS, Belinda ; GREENE, A. ; SANDERSON, C. R.
European journal of pain, 15/02/2020, Pagination inconnue

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Nurses' knowledge of law at the end of life and implications for practice - a qualitative study

WILLMOTT, Lindy ; WHITE, Ben ; YATES, Patsy ; MITCHELL, Geoffrey ; CURROW, David ; GERBER, Katrin ; PIPER, Donella
PALLIATIVE MEDICINE, 07/02/2020, Pagination inconnue

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Role of hospice care at the end of life for people with cancer

CURROW, David ; AGAR, Meera R. ; PHILLIPS, Jane L.
Journal of clinical oncology, 05/02/2020, Pagination inconnue

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Standards, guidelines, and quality measures for successful specialty palliative care integration into oncology - current approaches and future directions

KAMAL, Arif H. ; BAUSEWEIN, Claudia ; CASARETT, David J. ; CURROW, David ; DUDGEON, Deborah J. ; HIGGINSON, Irene J.
Journal of clinical oncology, 05/02/2020, Pagination inconnue

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Symptomatic events in a community palliative care population - a prospective pilot study

TO, Timothy H. M. ; COLLIER, Aileen ; AGAR, Meera R. ; ROWETT, Debra ; CURROW, David
JOURNAL OF PALLIATIVE MEDICINE, 08/01/2020, Pagination inconnue

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Pharmacovigilance in hospice/palliative care - de-prescribing combination controlled release oxycodone-naloxone

CLARK, Katherine ; BYRNE, Paul G. ; HUNT, Jane ; BROWN, Linda ; ROWETT, Debra ; WATTS, Gareth ; LOVELL, Melanie ; CURROW, David
JOURNAL OF PALLIATIVE MEDICINE, 03/01/2020, Pagination inconnue

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Is inpatient hospice care clinically effective? - using phase of illness to evaluate care outcomes for patients admitted to a specialist palliative care unit in Ireland

LUCEY, Michael ; O'REILLY, Martina ; CURROW, David ; EAGAR, Kathy ; WALSH, Declan ; CONROY, Marian ; TWOMEY, Feargal ; O'REILLY, Val ; DOHERTY, Mairéad ; COFFEY, Siobhain ; SHERIDAN, John ; MORAN, Sue
JOURNAL OF PALLIATIVE MEDICINE, 19/12/2019, Pagination inconnue

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Prevalence and severity of sleep difficulty in patients with a CNS cancer receiving palliative care in Australia

JEON, Megan S. ; DHILLON, Haryana M. ; DESCALLAR, Joseph ; LAM, Lawrence ; ALLINGHAM, Samuel ; KOH, Eng-Siew ; CURROW, David ; AGAR, Meera R.
Neuro-oncology practice, 12/2019, vol.6, n°6, p. 499-507

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The trajectory of functional decline over the last 4 months of life in a palliative care population - a prospective, consecutive cohort study

MORGAN, Deidre D. ; TIEMAN, Jennifer J. ; ALLINGHAM, Samuel F. ; EKSTROM, Magnus P. ; CONNOLLY, Alanna ; CURROW, David
PALLIATIVE MEDICINE, 06/2019, vol.33, n°6, p. 693-703

Intention-to-treat analyses for randomised controlled trials in hospice/palliative care - the case for analyses to be of people exposed to the intervention

KOCHOVSKA, Slavica ; HUANG, Chao ; JOHNSON, Miriam J. ; AGAR, Meera ; FALLON, Marie T. ; KAASA, Stein ; HUSSAIN, Jamilla A. ; PORTENOY, Russell K. ; HIGGINSON, Irene J. ; CURROW, David
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 03/2020, vol.599, n°3, p.

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Thème : Recherche - Evaluation - Méthodologie. Cote : e00.07JPS

ESSAI CONTROLE RANDOMISE ; UNITE SOINS PALLIATIFS ; DEMARCHE PALLIATIVE ; PARTICIPATION

INTRODUCTION: Minimising bias in randomised controlled trials (RCTs) includes intention-to-treat (ITT) analyses. Hospice/palliative care RCTs are constrained by high attrition unpredictable when consenting, including withdrawals between randomisation and first exposure to the intervention. Such withdrawals may systematically bias findings away from the new intervention being evaluated if they are considered non-responders. This study aimed to quantify this impact within ITT principles.
METHODS: A theoretical model was developed to assess the impact of withdrawals between randomisation and first exposure on i) study power and ii) effect sizes. Ten reported hospice/palliative care studies had power recalculated accounting for such withdrawal.
RESULTS: In the theoretical model, when 5% of withdrawals occurred between randomisation and first exposure to the intervention, change in power was demonstrated in binary outcomes (2.0-2.2%), continuous outcomes (0.8-2.0%) and time-to-event outcomes (1.6-2.0%), and odds ratios were changed by 0.06-0.17. Greater power loss was observed with larger effect sizes. Withdrawal rates were 0.9%-10% in the ten reported RCTs, corresponding to power losses of 0.1%-2.2%. For studies with binary outcomes, withdrawal rates were 0.3-1.2%, changing odds ratios by 0.01-0.22.
DISCUSSION: If blinding is maintained and all interventions are available simultaneously, our model suggests that excluding data from withdrawals between randomisation and first exposure to the intervention minimises one bias. This is the safety population as defined by the International Committee on Harmonisation. When planning for future trials, minimising the time between randomisation and first exposure to the intervention will minimise the problem. Power should be calculated on people who receive the intervention.

Origine : PubMed

""Through the eyes of the dying" - identifying who may benefit from bereavement follow-up: a qualitative study

PHILLIPS, Jane L. ; LOBB, Elizabeth A. ; BELLEMORE, Frances ; HAYS, Terrence ; CURROW, David
Collegian, 05/10/2019, Pagination inconnue

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Mental wellbeing in bereaved carer - a health survey for England population study

HODIAMONT, Farina ; ALLGAR, Victoria ; CURROW, David ; JOHNSON, Miriam J.
BMJ supportive and palliative care, 06/09/2019, Pagination inconnue

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Methotrimeprazine versus haloperidol in palliative care patients with cancer-related nausea - a randomised, double-blind controlled trial

HARDY, Janet Rea ; SKERMAN, Helen ; PHILIP, Jennifer ; GOOD, Phillip ; CURROW, David ; MITCHELL, Geoffrey ; YATES, Patsy
BMJ Open, 12/09/2019, vol.9, n°9, p. 1-9

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Palliative care for people living with heart failure - European Association for Palliative Care Task Force expert position statement

SOBANSKI, Piotr Z. ; ALT-EPPING, Bernd ; CURROW, David ; GOODLIN, Sarah J. ; GRODZICKI, Tomasz ; HOGG, Karen ; JANSSEN, Daisy J. A. ; JOHNSON, Miriam J. ; KRAJNIK, Malgorzata ; LEGET, Carlo ; MARTÍNEZ-SELLES, Manuel ; MORONI, Matteo ; MUELLER, Paul S. ; RYDER, Mary ; SIMON, Steffen T. ; STOWE, Emily ; LARKIN, Philip J.
Cardiovascular research, 06/08/2019, p. 1-16

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Use of time in people with a life-limiting illness - a longitudinal cohort feasibility pilot study

JONES, Terry A. ; OLDS, Timothy S. ; CURROW, David ; WILLIAMS, Marie T.
PALLIATIVE MEDICINE, 01/08/2019, Pagination inconnue

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The association between glycemic control in people with diabetes and symptoms at the end of life - a prospective observational consecutive cohort study

KLEINIG, Paul A. ; WOODMAN, Richard J. ; CURROW, David
JOURNAL OF PALLIATIVE MEDICINE, 13/08/2019, Pagination inconnue

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Clustering of 27,525,663 death records from the United States based on health conditions associated with death - an example of big health data exploration

JANSSEN, Daisy J. A. ; RECHBERGER, Simon ; WOUTERS, Emiel F. M. ; SCHOLS, Jos M. G. A. ; JOHNSON, Miriam J. ; CURROW, David ; CURTIS, J. Randall ; SPRUIT, Martijn A.
Journal of clinical medicine, 27/06/2019, vol.8, n°7, p. 1-15

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