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ACHARNEMENT THERAPEUTIQUE

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Validation of the NUE rule to predict futile resuscitation of out-of-hospital cardiac arrest

GLOBER, Nancy K. ; LARDARO, Thomas ; CHRISTOPHER, Shawn ; TAINTER, Christopher R. ; WEINSTEIN, Elizabeth ; KIM, David
Prehospital emergency care, 28/10/2020, p. 1-6

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Perceptions of futility in interventional radiology - a multipractice systematic qualitative analysis

KELLER, Eric J. ; RABEI, Rana ; HELLER, Michael ; KOTHARY, Nishita
Cardiovascular and interventional radiology, 19/10/2020, Pagination inconnue

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Ethical and legal considerations related to disorders of consciousness

RISSMAN, Lauren ; PAQUETTE, Erin Talati
Current opinion in pediatrics, 12/2020, vol.32, n°6, p. 765-771

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One last round of chemo? - insights from conversations between oncologists and lung cancer patients about prognosis and treatment decisions

HAUGE, Amalie M.
Social science and medicine, 04/10/2020, vol.266, Pagination inconnue

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End-of-life (EOL) comfort care and withdrawal of life support (WLS) of severely burned patients - a review of the literature

ATIYEH, B.
Annals of burns and fire disasters, 30/06/2020, vol.33, n°2, p. 154-161

Futility in the paediatric cardiac ICU

FUNDORA, Michael P. ; RODRIGUEZ, Zahidee ; MAHLE, William T.
Cardiology in the young, 24/07/2020, p. 1-8

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A stepped-wedge randomised-controlled trial assessing the implementation, impact and costs of a prospective feedback loop to promote appropriate care and treatment for older patients in acute hospitals at the end of life - study protocol

LEE, Xing J. ; FARRINGTON, Alison ; CARTER, Hannah ; SHIELD, Carla ; GRAVES, Nicholas ; MCPHAIL, Steven M. ; HARVEY, Gillian ; WHITE, Ben P. ; WILLMOTT, Lindy ; CARDONA, Magnolia ; HILLMAN, Ken ; CALLAWAY, Leonie ; BARNETT, Adrian G.
BMC GERIATRICS, 29/07/2020, vol.20, n°1, p. 1-9

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Getting the balance right - medical futility, scientific advancement, and the role of law

GLOVER-THOMAS, Nicola
Medical law review, 31/07/2020, Pagination inconnue

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HIV and lymphoma - from oncological futility to treatment

NOY, Ariela
The lancet. HIV, 10/08/2020, vol.7, n°9, p. e598-e600

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Frailty status predicts futility of cardiopulmonary resuscitation in older adults

IBITOYE, Sarah E ; RAWLINSON, Sadie ; CAVANAGH, Andrew ; PHILLIPS, Victoria ; SHIPWAY, David J H
Age and ageing, 05/06/2020, Pagination inconnue

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Perceptions of intensive care unit nurses of therapeutic futility - a scoping review

VIEIRA, João V. ; DEODATO, Sérgio ; MENDES, Felismina
Clinical ethics, 09/06/2020, Pagination inconnue

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Prognosis and futility in neurosurgical emergencies - a review

ANDERSON, Emily ; KRYZANSKI, James
Clinical neurology and neurosurgery, 07/05/2020, vol.195, Pagination inconnue

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Meaningful futility - requests for resuscitation against medical recommendation

VIVAS, Lucas ; CARPENTER, Travis
Journal of medical ethics, 24/04/2020, p. 1-3

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When can muslims withdraw or withhold life support? - a narrative review of islamic juridical rulings

MOHIUDDIN, Afshan ; SULEMAN, Mehrunisha ; RASHEED, Shoaib ; PADELA, Aasim I.
Global bioethics, 01/01/2020, vol.31, n°1, p. 29-46

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Death by decade - establishing a transfusion ceiling for futility in massive transfusion

MORRIS, Mackenzie C. ; NIZIOLEK, Grace M. ; BAKER, Jennifer E. ; HUEBNER, Benjamin R. ; HANSEMAN, Dennis ; MAKLEY, Amy T. ; PRITTS, Timothy A. ; GOODMAN, Michael D.
Journal of surgical research, 08/2020, vol.252, p. 139-146

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Thème : Soins.

TRANSFUSION SANGUINE ; ACHARNEMENT THERAPEUTIQUE ; MORTALITE

Background: Age and massive transfusion are predictors of mortality after trauma. We hypothesized that increasing age and high-volume transfusion would result in progressively elevated mortality rates and that a transfusion “ceiling” would define futility.
Methods: The Trauma Quality Improvement Program (TQIP) database was queried for 2013-2016 records and our level I trauma registry was reviewed from 2013 to 2018. Demographic, mortality, and blood transfusion data were collected. Patients were grouped by decade of life and by packed red blood cell (pRBC) transfusion requirement (zero units, 1-3 units, or =4 units) within 4 h of admission.
Results: TQIP analysis demonstrated an in-hospital mortality risk that increased linearly with age, to an odds ratio of 10.1 in =80 y old ( P < 0.01). Mortality rates were significantly higher in older adults ( P < 0.01) and those with more pRBCs transfused. In massively transfused patients, the transfusion “ceiling” was dependent on age. Owing to the lack granularity in the TQIP database, 230 patients from our institution who received =4 units of pRBCs within 4 h of admission were reviewed. On arrival, younger patients had significantly higher heart rates and more severe derangements in lactate levels, base deficits, and pH compared with older patients. There were no differences among age groups in injury severity score, systolic blood pressure, or mortality.
Conclusions: In massively transfused patients, mortality increased with age. However, a significant proportion of older adults were successfully resuscitated. Therefore, age alone should not be considered a contraindication to high-volume transfusion. Traditional physiologic and laboratory criteria indicative of hemorrhagic shock may have reduced reliability with increasing age, and thus providers must have a heightened suspicion for hemorrhage in the elderly. Early transfusion requirements can be combined with age to establish prognosis to define futility to help counsel families regarding mortality after traumatic injury.

Origine : DOI.org (Crossref

Transcatheter aortic valve implantation-related futility - prevalence, predictors, and clinical risk model

HIGUCHI, Ryosuke ; SAJI, Mike ; HAGIYA, Kenichi ; TAKAMISAWA, Itaru ; SHIMIZU, Jun ; TOBARU, Tetsuya ; IGUCHI, Nobuo ; TAKANASHI, Shuichiro ; TAKAYAMA, Morimasa ; ISOBE, Mitsuaki
Heart and vessels, 06/04/2020, Pagination inconnue

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Australian policies on "futile" or "non-beneficial" treatment at the end of life - a qualitative content analysis

CLOSE, Eliana ; PARKER, Malcolm ; WILLMOTT, Lindy ; WHITE, Ben ; CROWDEN, Andrew
Journal of law and medicine, 12/2019, vol.27, n°2, p. 415-439

When does treatment in cancer care become futile?

KATZ, Pamela
Clinical journal of oncology nursing, 01/02/2020, vol.24, n°1, p. 111

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Reconsidering requests - futility in IR

CLARK, Jessica M. ; KELLER, Eric J.
Journal of vascular and interventional radiology, 06/2019, vol.30, n°6, p. 961-962

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Perception of provision of futile care among clinicians in the neuroscience intensive care unit

AMOROSO, Shanna ; CHALELA, Julio A.
The journal of neuroscience nursing, 10/2019, vol.51, n°5, p. 249-252

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