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Alternative consent models in pragmatic palliative care clinical trials

CARPENTER, Joan G. ; ULRICH, Connie ; HODGSON, Nancy ; HANSON, Laura C. ; ERSEK, Mary
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 28/10/2020, Pagination inconnue

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Nothing to lose - a grounded theory study of patients' and healthcare professionals' perspectives of being involved in the consent process for oncology trials with non-curative intent

MURPHY, Mary ; MCCAUGHAN, Eilís ; CARSON, Matthew A. ; DONOVAN, Monica ; WILSON, Richard H. ; FITZSIMONS, Donna
BMC palliative care, 30/10/2020, vol.19, n°1, p. 1-10

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Processes of consent in research for adults with impaired mental capacity nearing the end of life - systematic review and transparent expert consultation (MORECare_Capacity statement)

EVANS, C. J. ; YORGANCI, E. ; LEWIS, P. ; KOFFMAN, J. ; STONE, K. ; TUNNARD, I. ; WEE, Bee ; BERNAL, W. ; HOTOPF, M. ; HIGGINSON, I. J. ; MORECARE_CAPACITY
BMC medicine, 22/07/2020, vol.18, n°1, p. 1-55

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Usage of do-not-attempt-to-resuscitate orders in a Swedish community hospital - patient involvement, documentation and compliance

BERTILSSON, Emilie ; SEMARK, Birgitta ; SCHILDMEIJER, Kristina ; BREMER, Anders ; CARLSSON, Jörg
BMC medical ethics, 01/08/2020, vol.21, n°1, p. 1-6

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The capacity to consent to treatment in Amyotrophic Lateral Sclerosis - a preliminary report

SPATARO, Rossella ; LA BELLA, Vincenzo
Journal of neurology, 06/08/2020, Pagination inconnue

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Factors influencing consent rates of deceased organ donation in Western Cape province, South Africa

BOOKHOLANE, H. ; MICHAELIDES, A. ; PRINS, L. ; STEENKAMP, L. ; GILI, B. ; MCCURDIE, F. ; HUMAN, L. ; THOMSON, D.
South African medical journal, 26/02/2020, vol.110, n°3, p. 204-209

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Prélèvements d’organe selon la procédure Maastricht III - nos garde-fous éthiques sont-ils suffisants ?

ROBERT, René ; PAIN, Benoît
Médecine intensive réanimation, 01/03/2020, vol.29, n°1, p. 3-6

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Procédure maastricht 3 - restons attentifs à ses enjeux éthiques !

BOYER, A. ; PENVEN, G. ; QUENTIN, B. ; SILVA, S. ; THIERY, G.
Médecine intensive réanimation, 01/03/2020, vol.29, n°1, p. 7-16

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Knowledge, opinion and attitude about the Italian law on advance directives - a population-based survey

DE PANFILIS, Ludovica ; ROSSI, Paolo Giorgi ; MAZZINI, Elisa ; PISTOLESI, Luca ; GHIROTTO, Luca ; NOTO, Antonio ; CUOCOLO, Sandra ; COSTANTINI, Massimo
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 30/06/2020, p. 1-35

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Is informed consent required for the diagnosis of brain death regardless of consent for organ donation?

MURAMOTO, Osamu
Journal of medical ethics, 05/06/2020, Pagination inconnue

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L'éthique médicale et la bioéthique

SICARD, Didier
PUF , 06/2020 , 125 p.

Refus de soins et responsabilité

MEL, Emmanuelle
REVUE DE L'INFIRMIERE, 02/2020, vol.69, n°258, p. 25-26

Characteristics of parental decision-making for children with advanced cancer who are offered enrollment in early-phase clinical trials - a systematic review

LE ROUZIC, Marie-Amelyne ; CLAUDOT, Frédérique
Pediatric hematology and oncology, 13/05/2020, p. 1-30

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Use of combined do-not-resuscitate/do-not intubate orders without documentation of intubation preferences - a retrospective observational study at an academic level 1 trauma center

RUBINS, Jeffrey B.
Chest, 25/02/2020, Pagination inconnue

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Thème : Ethique et déontologie.

TESTAMENT VIE ; ETUDE RETROSPECTIVE ; INFORMATION MALADE ; CONSENTEMENT

BACKGROUND: Combining orders for do-not-resuscitate (DNR) for cardiac arrest with do-not-intubate (DNI) orders into a DNR/DNI code status is not evidence-based practice and may violate patient autonomy and informed consent when providers discuss intubation only in the context of CPR.
RESEARCH QUESTION: How often do providers refer to patients with a DNR order as "DNR/DNI" without documentation of refusal of intubation for non-arrest situations?
STUDY DESIGN AND METHODS: Retrospective observational study of adults (18 years or older) hospitalized in a Level 1 trauma/academic hospital between July 2017 and June 2018 inclusive with DNR orders placed during hospitalization RESULTS: Of 422 hospitalized adults with DNR orders, 261 (61.9%) had code status written in progress notes as DNR/DNI. Providers' use of the term DNR/DNI in progress notes was significantly (OR 2.21 99% CI 1.12 - 4.37) more common on medical hospital services (hospitalist, family medicine, internal medicine) than on non-medical ward services (medical/surgical intensive care units, surgery, psychiatry, neurology services).Of 261 "DNR/DNI"patients, providers did not document informed refusal of intubation for non-arrest situations for 68 (26.0%) of patients. By comparison, of 161 patients where providers documented code status in progress notes as DNR alone, 69 (42.9%) did have documentation of refusal of intubation for non-arrest events. Therefore, if a DNR/DNI code status was used in a non-arrest emergency to determine whether to intubate a patient, 68 (16.1%) of 422 patients could inappropriately be denied intubation without informed refusal (or despite their informed acceptance), and 69 (16.4%) could inappropriately be intubated despite their documented refusal of intubation.
INTERPRETATION: Conflation of DNR and DNI into DNR/DNI does not reliably distinguish patients who refuse or accept intubation for indications other than cardiac arrest, and thus may inappropriately deny desired intubation for those who would accept it, and inappropriately impose intubation on patients who would not.

Origine : PubMed

Assessment of the decision-making capacity for clinical research participation in patients with advanced cancer in the last weeks of life

GOSWAMI, Rachna ; MOORE, Jessica ; BRUERA, Eduardo ; HUI, David
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 24/02/2020, Pagination inconnue

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Respect for autonomy in systems of postmortem organ procurement - a comment

DEN HARTOGH, Govert
Bioethics, 01/01/2019, vol.33, n°5, p. 550-556

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What are two days worth? - facing dilemmas together at the end of life

ROSENBERG, Leah B.
The New England journal of medicine, 05/03/2020, vol.382, n°10, p. 890-891

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The culture of hope and ethical challenges in clinical trials - a qualitative study of oncologists and haematologists’ views

GODSKESEN, Tove E ; PETRI, Suzanne ; ERIKSSON, Stefan ; HALKOAHO, Arja ; MANGSET, Margrete ; NIELSEN, Zandra E
Clinical ethics, 30/12/2019, p. 1-10

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Withdrawing treatment from patients with prolonged disorders of consciousness - the wrong answer is what the wrong question begets

WANG, Daniel Wei Liang
Journal of medical ethics, 13/02/2020, Pagination inconnue

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Can there be wrongful life at the end of life? - German courts revisit an old problem in a new context

PFEIFER, Ulrich ; HORN, Ruth
Journal of medical ethics, 14/02/2020, Pagination inconnue

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