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DELIENS, Luc

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Healthcare interventions improving and reducing quality of life in children at the end of life - a systematic review

PIETTE, Veerle ; BEERNAERT, Kim ; COHEN, Joachim ; PAUWELS, Nele S. ; SCHERRENS, Anne-Lore ; VAN DER WERFF TEN BOSCH, Jutte ; DELIENS, Luc
Pediatric research, 09/07/2020, Pagination inconnue

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Thème : Soins.

BELGIQUE ; ENFANT ; QUALITE VIE ; FIN VIE ; REVUE SYSTEMATIQUE

BACKGROUND: Children with serious illness suffer from symptoms at the end of life that often fail to be relieved. An overview is required of healthcare interventions improving and decreasing quality of life (QOL) for children with serious illness at the end of life.
METHODS: A systematic review was performed in five databases, January 2000 to July 2018 without language limit. Reviewers selected quantitative studies with a healthcare intervention, for example, medication or treatment, and QOL outcomes or QOL-related measures, for example, symptoms, for children aged 1-17 years with serious illness. One author assessed outcomes with the QualSyst and GRADE (Grades of Recommendation, Assessment, Development, and Evaluation) Framework; two authors checked a 25% sample. QOL improvement or reduction was categorized.
RESULTS: Thirty-six studies met the eligibility criteria studying 20 unique interventions. Designs included 1 randomized controlled trial, 1 cross-sectional study, and 34 cohort studies. Patient-reported symptom monitoring increased QOL significantly in cancer patients in a randomized controlled trial. Dexmedetomidine, methadone, ventilation, pleurodesis, and palliative care were significantly associated with improved QOL, and chemotherapy, stem cell transplant, and hospitalization with reduced QOL, in cohort studies.
CONCLUSIONS: Use of patient-controlled symptom feedback, multidisciplinary palliative care teams with full-time practical support, inhalation therapy, and off-label sedative medication may improve QOL. Curative therapy may reduce QOL.
IMPACT: QOL for children at the end of life may be improved with patient-controlled symptom feedback, multidisciplinary palliative care teams with full-time practical support, inhalation therapy, and off-label sedative medication.QOL for children at the end of life may be reduced with therapy with a curative intent, such as curative chemotherapy or stem cell transplant.A comprehensive overview of current evidence to elevate currently often-failing QOL management for children at the end of life.New paradigm-level indicators for appropriate and inappropriate QOL management in children at the end of life.New hypotheses for future research, guided by the current knowledge within the field.Various healthcare interventions (as described above) could or might be employed as tools to provide relief in QOL management for children with serious illness, such as cancer, at the end of life, and therefore could be discussed in pediatrician end-of-life training to limit the often failed QOL management in this population, cave the one-size-fits-all approach for individual cases.Multidisciplinary team efforts and 24/7 presence, especially practical support for parents, might characterize effective palliative care team interventions for children with serious illness at the end of life, suggesting a co-regulating link between well-being of the child partly to that of the parentsHypothesis-oriented research is needed, especially for children with nonmalignant disorders, such as genetic or neurological disorders at the end of life, as well as QOL outcomes for intervention research and psychosocial or spiritual outcomes.

Origine : PubMed

The perception of people with cancer of starting a conversation about palliative care - a qualitative interview study

SCHERRENS, Anne-Lore ; COHEN, Joachim ; MAHIEU, Annick ; DELIENS, Luc ; DEFORCHE, Benedicte ; BEERNAERT, Kim
European journal of cancer care, 01/07/2020, Pagination inconnue

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Nurses' self-efficacy, rather than their knowledge, is associated with their engagement in advance care planning in nursing homes - a survey study

GILISSEN, Joni ; PIVODIC, Lara ; WENDRICH-VAN DAEL, Annelien ; COOLS, Wilfried ; VANDER STICHELE, Robert ; VAN DEN BLOCK, Lieve ; DELIENS, Luc ; GASTMANS, Chris
PALLIATIVE MEDICINE, 08/05/2020, Pagination inconnue

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End-of-life communication in advanced cancer - international trends (2009-2014)

VERKISSEN, Mariëtte N. ; PENDERS, Yolanda W. H. ; ONWUTEAKA-PHILIPSEN, Bregje D. ; MOREELS, Sarah ; DONKER, Gé A. ; VEGA ALONSO, Tomás ; VAN DEN BLOCK, Lieve ; DELIENS, Luc
BMJ supportive and palliative care, 27/04/2020, Pagination inconnue

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Trends in place of death in a small developing country - a population-level study using death certificate data

JENNINGS, Nicholas ; CHAMBAERE, Kenneth ; DELIENS, Luc ; COHEN, Joachim
Journal of epidemiology and community health, 22/04/2020, Pagination inconnue

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Opioid underuse in terminal care of long-term care facility residents with pain and/or dyspnoea - a cross-sectional pace-survey in six European countries

TANGHE, Marc ; VAN DEN NOORTGATE, Nele ; DELIENS, Luc ; SMETS, Tinne ; ONWUTEAKA-PHILIPSEN, Bregje ; SZCZERBINSKA, Katarzyna ; FINNE-SOVERI, Harriet ; PAYNE, Sheila ; GAMBASSI, Giovanni ; VAN DEN BLOCK, Lieve ; PIERS, Ruth
PALLIATIVE MEDICINE, 14/04/2020, Pagination inconnue

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Comparing symptom ratings by staff and family carers in residents dying in long-term care facilities in three European countries, results from a PACE-survey

TANGHE, Marc ; VAN DEN NOORTGATE, Nele ; DELIENS, Luc ; SMETS, Tinne ; ONWUTEAKA-PHILIPSEN, Bregje ; FINNE-SOVERI, Harriet ; VAN DEN BLOCK, Lieve ; PIERS, Ruth
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 10/03/2020, Pagination inconnue

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Comfort and clinical events at the end of life of nursing home residents with and without dementia - the six-country epidemiological PACE study

MIRANDA, Rose ; VAN DER STEEN, Jenny T. ; SMETS, Tinne ; VAN DEN NOORTGATE, Nele ; DELIENS, Luc ; PAYNE, Sheila ; KYLANEN, Marika ; SZCZERBINSKA, Katarzyna ; GAMBASSI, Giovanni ; VAN DEN BLOCK, Lieve ; PACE
International journal of geriatric psychiatry, 03/03/2020, Pagination inconnue

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Earlier palliative home care is associated with patient-centered medical resource utilisation and lower costs in the last 30 days before death in COPD - a population-level decedent cohort study

SCHEERENS, Charlotte ; FAES, Kristof ; PYPE, Peter ; BEERNAERT, Kim ; JOOS, Guy ; DEROM, Eric ; COHEN, Joachim ; DELIENS, Luc ; CHAMBAERE, Kenneth
The European respiratory journal, 27/02/2020, Pagination inconnue

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Appropriateness of end-of-life care in people dying with dementia - applying quality indicators on linked administrative databases

DE SCHREYE, Robrecht ; SMETS, Tinne ; DELIENS, Luc ; ANNEMANS, Lieven ; GIELEN, Birgit ; COHEN, Joachim
Journal of the American Medical Directors Association, 06/02/2020, Pagination inconnue

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Coping strategies of patients with advanced lung or colorectal cancer in six European countries - insights from the ACTION study

JABBARIAN, Lea J. ; KORFAGE, Ida J. ; CERV, Branka ; VAN DELDEN, Johannes J. M. ; DELIENS, Luc ; MICCINESI, Guido ; PAYNE, Sheila ; THIT JOHNSEN, Anna ; VERKISSEN, Mariëtte N. ; WILCOCK, Andrew ; VAN DER HEIDE, Agnes ; RIETJENS, Judith A. C. ; ACTION CONSORTIUM
Psycho-oncology, 02/2020, vol.29, n°2, p. 347-355

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Implementing the theory-based advance care planning ACP+ programme for nursing homes - study protocol for a cluster randomised controlled trial and process evaluation

GILISSEN, Joni ; PIVODIC, Lara ; WENDRICH-VAN DAEL, Annelien ; GASTMANS, Chris ; VANDER STICHELE, Robert ; ENGELS, Yvonne ; VERNOOIJ-DASSEN, Myrra JFJ. ; DELIENS, Luc ; VAN DEN BLOCK, Lieve
BMC palliative care, 08/01/2020, vol.19, n°1, p. 1-18

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Balancing medication use in nursing home residents with life-limiting disease

PAQUE, Kristel ; ELSEVIERS, Monique ; VANDER STICHELE, Robert ; PARDON, Koen ; VINKEROYE, Cinzia ; DELIENS, Luc ; CHRISTIAENS, Thierry ; DILLES, Tinne
European journal of clinical pharmacology, 07/2019, vol.75, n°7, p. 969-977

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The effect of early and systematic integration of palliative care in oncology on quality of life and health care use near the end of life - a randomised controlled trial

VANBUTSELE, Gaëlle ; VAN BELLE, Simon ; SURMONT, Veerle ; DE LAAT, Martine ; COLMAN, Roos ; EECLOO, Kim ; NAERT, Eline ; DE MAN, Marc ; GEBOES, Karen ; DELIENS, Luc ; PARDON, Koen
EUROPEAN JOURNAL OF CANCER, 01/2020, vol.124, p. 186-193

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Barriers in the decision making about and performance of continuous sedation until death in nursing homes

ROBIJN, Lenzo ; DELIENS, Luc ; RIETJENS, Judith ; PYPE, Peter ; CHAMBAERE, Kenneth
The gerontologist, 18/12/2019, Pagination inconnue

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Psychological support in end-of-life decision-making in neonatal intensive care units - full population survey among neonatologists and neonatal nurses

DOMBRECHT, Laure ; COHEN, Joachim ; COOLS, Filip ; DELIENS, Luc ; GOOSSENS, Linde ; NAULAERS, Gunnar ; BEERNAERT, Kim ; CHAMBAERE, Kenneth ; NICU CONSORTIUM
PALLIATIVE MEDICINE, 19/11/2019, Pagination inconnue

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International variations in clinical practice guidelines for palliative sedation - a systematic review

ABARSHI, Ebun ; RIETJENS, Judith ; ROBIJN, Lenzo ; CARACENI, Augusto ; PAYNE, Sheila ; DELIENS, Luc ; VAN DEN BLOCK, Lieve ; EURO IMPACT
BMJ supportive and palliative care, 01/01/2017, vol.7, n°3, p. 223-229

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The use of behavioural theories in end-of-life care research - a systematic review

SCHERRENS, Anne-Lore ; BEERNAERT, Kim ; ROBIJN, Lenzo ; DELIENS, Luc ; PAUWELS, Nele S. ; COHEN, Joachim ; DEFORCHE, Benedicte
PALLIATIVE MEDICINE, Sage publications, 06/2018, vol.32, n°6, 1055-1077

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Barriers to and facilitators of end-of-life decision-making by neonatologists and neonatal nurses in neonates - a qualitative study

DOMBRECHT, Laure ; PIETTE, Veerle ; DELIENS, Luc ; COOLS, Filip ; CHAMBAERE, Kenneth ; GOOSSENS, Linde ; NAULAERS, Gunnar ; CORNETTE, Luc ; BEERNAERT, Kim ; COHEN, Joachim ; NICU CONSORTIUM
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 03/2020, vol.59, n°3, p. 599-608.e2

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