VigiPallia : Résultats

SONG, Hong Suk

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Treatment patterns and changes in quality of life during first-line palliative chemotherapy in Korean patients with advanced gastric cancer

KIM, Jin Won ; KIM, Jong Gwang ; KANG, Byung Woog ; CHUNG, Ik-Joo ; HONG, Young Seon ; KIM, Tae-You ; SONG, Hong Suk ; LEE, Kyung Hee ; ZANG, Dae Young ; KO, Yoon Ho ; SONG, Eun-Kee ; BAEK, Jin Ho ; KOO, Dong-Hoe ; OH, So Yeon ; CHO, Hana ; LEE, Keun-Wook
Cancer research and treatment, 2019, vol.51, n°1, p. 223-239

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Thème : Recherche - Evaluation - Méthodologie. Cote : eD15.00.02.02

CHIMIOTHERAPIE ; CANCER DIGESTIF ; COREE ; QUALITE VIE

Purpose: The purpose of this study was to evaluate chemotherapy patterns and changes in quality of life (QOL) during first-line palliative chemotherapy for Korean patients with unresectable or metastatic/recurrent gastric cancer (GC).
Materials and Methods: This was a non-interventional, multi-center, prospective, observational study of 527 patients in Korea. QOL assessments were conducted using the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaires (QLQ)-C30 and QLQ-STO22 every 3 months over a 12-month period during first-line palliative chemotherapy. The specific chemotherapy regimens were selected by individual clinicians.
Results: Most patients (93.2%) received combination chemotherapy (mainly fluoropyrimidine plus platinum) as their first-line palliative chemotherapy. The median progression-free survival and overall survival were 8.2 and 14.8 months, respectively. Overall, “a little” changes (differences of 5-10 points from baseline) were observed in some of the functioning or symptom scales; none of the QOL scales showed either “moderate” or “very much” change (i.e., = 11 point difference from baseline). When examining the best change in each QOL domain from baseline, scales related to some aspects of functioning, global health status/QOL, and most symptoms revealed significant improvements (p < 0.05). Throughout the course of first-line palliative chemotherapy, most patients’ QOL was maintained to a similar degree, regardless of their actual response to chemotherapy.
Conclusion: This observational study provides important information on the chemotherapy patterns and QOL changes in Korean patients with advanced GC. Overall, first-line palliative chemotherapy was found to maintain QOL, and most parameters showed an improvement compared with the baseline at some point during the course.

Origine : PubMed

Predicting cumulative incidence of adverse events in older patients with cancer undergoing first-line palliative chemotherapy - Korean cancer study group (KCSG) multicentre prospective study

KIM, Jin Won ; LEE, Yun-Gyoo ; HWANG, In Gyu ; SONG, Hong Suk ; KOH, Su Jin ; KO, Yoon Ho ; SHIN, Seong Hoon ; WOO, In Sook ; HONG, Soojung ; KIM, Tae-Yong ; KIM, Sun Young ; NAM, Byung-Ho ; KIM, Hyun Jung ; KIM, Hyo Jung ; LEE, Myung Ah ; KWON, Jung Hye ; HONG, Yong Sang ; BAE, Sung Hwa ; KOO, Dong-Hoe ; KIM, Kwang-Il ; KIM, Jee Hyun
British journal of cancer, 26/03/2018, Pagination inconnue

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The impact of caregiver's role preference on decisional conflicts and psychiatric distresses in decision making to help caregiver's disclosure of terminal disease status

YOO, Shin Hye ; YUN, Young Ho ; KIM, Kyoung-Nam ; LEE, Jung Lim ; PARK, Jeanno ; CHOI, Youn Seon ; LIM, Yeun Keun ; KIM, Samyong ; JEONG, Hyun Sik ; KANG, Jung Hun ; OH, Ho-Suk ; PARK, Ji Chan ; KIM, Si-Young ; SONG, Hong Suk ; LEE, Keun Seok ; HEO, Dae Seog ; HONG, Young Seon
Quality of life research, 24/02/2018, p. 1-11

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Use of a decision aid to help caregivers discuss terminal disease status with a family member with cancer - a randomized controlled trial

YUN, Young Ho ; LEE, Myung Kyung ; PARK, Sohee ; LEE, Jung Lim ; PARK, Jeanno ; CHOI, Youn Seon ; LIM, Yeun Keun ; KIM, Sam Yong ; JEONG, Hyun Sik ; KANG, Jung Hun ; OH, Ho-Suk ; PARK, Ji Chan ; KIM, Si-Young ; SONG, Hong Suk ; RO, Jungsil ; LEE, Keun Seok ; HEO, Dae Seog ; HONG, Young Seon
Journal of clinical oncology, 20/12/2011, vol.29, n°36, p. 4811-4819

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