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Evaluating end-of-life chemotherapy for solid tumor and hematologic malignancy patients

VAN METREBAUM, Laura ; ROSENBLUM, Rachel ; SCARBOROUGH, Bethann ; SMITH, Cardinale B.
PROGRESS IN PALLIATIVE CARE, 24/01/2021, p. 1-5

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Impact of intervention aimed at improving the integration of oncology units and local palliative care services - results of the multicentre prospective sequential MIRTO study

MARTONI, Andrea A. ; MELOTTI, Barbara ; DEGLI ESPOSTI, Claudia ; MUTRI, Vita ; LELLI, Giorgio ; ANSALONI, Silvia ; PIVA, Erico ; STROCCHI, Elena ; PANNUTI, Franco
ESMO open, 01/01/2017, vol.2, n°1, p. 1-9

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Use of palliative chemotherapy and ICU admissions in gastric and esophageal cancer patients in the last phase of life - a nationwide observational study

BESSELING, Joost ; REITSMA, Jan ; VAN ERKELENS, Judith A. ; SCHEPENS, Maike H. J. ; SIROEN, Michiel P. C. ; ZIEDSES DES PLANTES, Cathelijne M. P. ; VAN BERGE HENEGOUWEN, Mark I. ; BEEREPOOT, Laurens V. ; VAN VOORTHUIZEN, Theo ; VAN ZUYLEN, Lia ; VERHOEVEN, Rob H. A. ; VAN LAARHOVEN, Hanneke
Cancers, 05/01/2021, vol.13, n°1, p. 1-10

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First-line palliative chemotherapy for esophageal and gastric cancer - practice patterns and outcomes in the general population

MERCHANT, Shaila J. ; KONG, Weidong ; GYAWALI, Bishal ; HANNA, Timothy P. ; CHUNG, Wiley ; NANJI, Sulaiman ; PATEL, Sunil V. ; BOOTH, Christopher M.
JCO oncology practice, 15/01/2021, Pagination inconnue

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A multicenter retrospective review of systemic anti-cancer treatment and palliative care provided to solid tumor oncology patients in the 12 weeks preceding death in Ireland

MALLETT, Victoria ; LINEHAN, Anna ; BURKE, Orla ; HEALY, Laura ; PICARDO, Sara ; KELLY, Catherine M. ; MCCAFFREY, John ; CARNEY, Des ; MCDERMOTT, Ray ; WALSHE, Janice ; KELLEHER, Fergal ; HIGGINS, Stephen ; RYAN, Karen ; HIGGINS, Michaela J.
The American journal of hospice and palliative care, 13/01/2021, Pagination inconnue

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Prospective evaluation of metabolic intratumoral heterogeneity in patients with advanced gastric cancer receiving palliative chemotherapy

YOO, Shin Hye ; KANG, Seo Young ; YOON, Jeesun ; KIM, Tae-Yong ; CHEON, Gi Jeong ; OH, Do-Youn
Scientific reports, 12/01/2021, vol.11, n°1, p. 1-11

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Effects of a patient-tailored integrative oncology intervention in the relief of pain in palliative and supportive cancer care

BEN-ARYE, Eran ; ELLY, Dana ; SAMUELS, Noah ; GRESSEL, Orit ; SHULMAN, Katerina ; SCHIFF, Elad ; LAVIE, Ofer ; MINERBI, Amir
Journal of cancer research and clinical oncology, 12/01/2021, Pagination inconnue

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Comparing clinician-assessed and patient-reported performance status for predicting morbidity and mortality in patients with advanced cancer receiving chemotherapy

WOOD, William A. ; DEAL, Allison M. ; STOVER, Angela M. ; BASCH, Ethan
JCO oncology practice, 08/01/2021, Pagination inconnue

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Duration of palliative care involvement and cancer care aggressiveness near the end of life

MONIER, Pierre Antoine ; CHRUSCIEL, Jan ; ECARNOT, Fiona ; BRUERA, Eduardo ; SANCHEZ, Stephane ; BARBARET, Cecile
BMJ supportive and palliative care, 21/12/2020, Pagination inconnue

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Intensity of care, expenditure, and place of death in French women in the year before their death from breast cancer - a population-based study

TANGUY-MELAC, Audrey ; DENIS, Pierre ; FAGOT-CAMPAGNA, Anne ; GASTALDI-MENAGER, Christelle ; LAURENT, Marie-Sylvie ; TUPPIN, Philippe
Cancer control, 12/2020, vol.27, n°1, p. 1-13

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Recurrent cervical cancer treated with palliative chemotherapy - real-world outcome

MAILANKODY, Sharada ; DHANUSHKODI, Manikandan ; GANESAN, Trivadi S ; RADHAKRISHNAN, Venkatraman ; CHRISTOPHER, Vasanth ; GANESHARAJAH, Selvaluxmy ; SAGAR, Tenali Gnana
Ecancermedicalscience, 13/10/2020, vol.14, p. 1-10

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Thème : Médecine. Cote : eD03.05.01

CANCER GENITAL ; CHIMIOTHERAPIE ; INDE ; ETUDE RETROSPECTIVE

Introduction: Cervical cancer is the third most common cancer in India. There is limited data on the treatment of relapsed cervical cancer from India; therefore, we report the outcomes of patients with recurrent cervical cancer who were treated with palliative chemotherapy (CT).
Materials and methods: This was a retrospective study of patients with recurrent cervical cancer who received palliative CT from January 2012 to December 2016. The demographic details, clinical profile and survival outcomes were collected. Patients were treated with carboplatin or paclitaxel and carboplatin. Local radiation was given for symptomatic patients. Patients were assessed for responses clinically and/or radiologically after three and six cycles of CT. Progression-free survival (PFS) and overall survival (OS) were calculated using the Kaplan–Meier method.
Results: Forty-six patients with recurrent cervical cancer were included in this analysis, with a median follow-up of 9.4 months. The median age was 49.5 (25–65) years and the median disease-free interval was 31.3 (2–196) months. Biopsy confirmation of relapse was established in 63%. The median number of CT cycles was six. Twenty-four (52.2%) patients completed six cycles of CT. The overall response rate was 56.5%. Patients with a complete or a partial response were more likely to have PFS > 6 months (p < 0.0001). Median PFS and OS were, respectively, 8.4 (95% CI 6.1–10.7) months and 10.3 (95% CI 6.8–13.8) months. The completion of all cycles of CT and the site of metastasis (nodal vs. visceral or combined) were found to be associated with OS.
Conclusion: Palliative CT with paclitaxel carboplatin is a safe and effective option in Indian patients with recurrent cervical cancer, with more than half of the patients completing the prescribed CT. Further prospective trials may be required to place this treatment in the right context, in this era of immunotherapy and targeted therapy. However, knowing the outcomes in our population and prognostic factors will help in better prognostication of patients, thereby channelling our limited resources where necessary.

Origine : PubMed Central

Early-onset pancreatic cancer - an institutional series evaluating end-of-life care

KADAKIA, Kunal C. ; TRUFAN, Sally J. ; JAGOSKY, Megan H. ; WORRILOW, William M. ; HARRISON, Bradley W. ; BROYHILL, Katherine L. ; HWANG, Jimmy J. ; MUSSELWHITE, Laura W. ; AKTAS, Aynur ; WALSH, Declan ; SALEM, Mohamed E.
Supportive care in cancer, 10/11/2020, Pagination inconnue

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How do claims-based measures of end-of-life care compare to family ratings of care quality?

CHRISTIAN, Thomas J. ; HASSOL, Andrea ; BROOKS, Gabriel A. ; GU, Qian ; KIM, Seyoun ; LANDRUM, Mary Beth ; KEATING, Nancy L.
Journal of the American Geriatrics Society, 09/11/2020, Pagination inconnue

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Identification of factors associated with aggressive end-of-life antitumour treatment - retrospective study of 1282 patients with cancer

DEBOURDEAU, Philippe ; BELKACEMI, Mohamed ; ECONOMOS, Guillaume ; ASSÉNAT, Eric ; HILGERS, Werner ; COUSSIROU, Julie ; UZAN, Sfaya Kouidri ; VASQUEZ, Léa ; DEBOURDEAU, Antoine ; DAURES, Jean Pierre ; SALAS, Sebastien
BMJ supportive and palliative care, 05/11/2020, Pagination inconnue

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Symptom evolution in patients with esophageal and gastric cancer receiving palliative chemotherapy - a population-based study

MERCHANT, Shaila J. ; KONG, Weidong ; BRUNDAGE, Michael ; BOOTH, Christopher M.
Annals of surgical oncology, 02/11/2020, Pagination inconnue

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Analysis of prognostic factors and design of prognosis model for patients with stage IV gastric cancer following first-line palliative chemotherapy

ZHOU, Qiyin ; LAN, Xi ; LI, Ni ; YUAN, Daozu ; ZHANG, Jiliang
Cancer management and research, 2020, vol.12, p. 10461-10468

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Chemotherapy in the last 30 days and 14 days of life in African Americans with lung cancer

JOHNSON, Lee Ann ; ELLIS, Charles
The American journal of hospice and palliative care, 28/10/2020, Pagination inconnue

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Too much too late? - chemotherapy administration at the end of life: a retrospective observational study

WILKERSON, David H. ; SANTOS, Jennifer L. ; TAN, Xiyan ; GOMEZ, Teny Henry
The American journal of hospice and palliative care, 28/10/2020, Pagination inconnue

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Chemotherapy use and quality of life in cancer patients at the end of life - an integrative review

AKHLAGHI, Elham ; LEHTO, Rebecca H. ; TORABIKHAH, Mohsen ; SHARIF NIA, Hamid ; TAHERI, Ahmad ; ZABOLI, Ehsan ; YAGHOOBZADEH, Ameneh
Health and quality of life outcomes, 2020, vol.18, n°1, p. 1-9

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