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ESSAI CONTROLE RANDOMISE

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Four conversations - a randomized controlled trial of an online, personalized coping, and decision aid for metastatic breast cancer patients

SMITH, Sophia K. ; WESTBROOK, Kelly ; MACDERMOTT, Kristin ; AMARASEKARA, Sarthya ; LEBLANC, Matthew ; PAN, Wei
JOURNAL OF PALLIATIVE MEDICINE, 22/10/2019, Pagination inconnue

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Fan therapy for the relief of dyspnea in adults with advanced disease and terminal illness - a meta-analysis of randomized controlled trials

YU, Shui ; SUN, Kai ; XING, Xiufang ; ZHONG, Yinbo ; YAN, Xuemei ; QIU, Weidong ; YAN, Min
JOURNAL OF PALLIATIVE MEDICINE, 01/10/2019, p. 1-7

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Effect of written outcome information on attitude of perinatal healthcare professionals at the limit of viability - a randomized study

PAPADIMITRIOU, V. ; TOSELLO, B. ; PFISTER, R.
BMC medical ethics, 22/10/2019, vol.20, n°1, p. 1-8

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Effectiveness of a self-monitoring quality of life intervention for patients with cancer receiving palliative care - a randomized controlled clinical trial

MATSUDA, Ayako ; YAMADA, Yosuke ; ISHIZUKA, Noriko ; MATSUSHIMA, Eisuke ; KOBAYASHI, Kunihiko ; OHKUBO, Takayoshi ; YAMAOKA, Kazue
Asian Pacific journal of cancer prevention, 01/09/2019, vol.20, n°9, p. 2795-2802

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Efficacy of nursing support in the pre- and postmedical termination of pregnancy phases - a randomized study

MECDI KAYDIRAK, Meltem ; ASLAN, Ergül
OMEGA JOURNAL OF DEATH AND DYING, 24/09/2019, Pagination inconnue

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Decision support intervention (Plan Well Guide) for patients and their substitute decision-makers to improve engagement in advance care planning - protocol for a randomised trial

HOWARD, Michelle ; SLAVEN, Marissa ; BERNARD, Carrie ; BORHAN, Sayem ; ELSTON, Dawn ; ARORA, Neha ; TAN, Amy ; HEYLAND, Daren K.
BMJ Open, 20/09/2019, vol.9, n°9, p. 1-8

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Advance care planning in frail older adult - a cluster randomized controlled trial

OVERBEEK, Anouk ; KORFAGE, Ida J. ; JABBARIAN, Lea J. ; BILLEKENS, Pascalle ; HAMMES, Bernard J. ; POLINDER, Suzanne ; SEVERIJNEN, Johan ; SWART, Siebe J. ; WITKAMP, Frederika E. ; VAN DER HEIDE, Agnes ; RIETJENS, Judith A. C.
Journal of the American Geriatrics Society, 01/01/2018, vol.66, n°6, p. 1089-1095

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Randomized controlled trial of SecondStory, an intervention targeting posttraumatic growth, with bereaved adults

ROEPKE, Ann Marie ; TSUKAYAMA, Eli ; FORGEARD, Marie ; BLACKIE, Laura ; JAYAWICKREME, Eranda
Journal of consulting and clinical psychology, 01/01/2018, vol.86, n°6, p. 518-532

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Thème : Deuil et travail du deuil.

SOUTIEN PSYCHOLOGIQUE ; PERSONNE ENDEUILLEE ; TRAUMATISME ; ESSAI CONTROLE RANDOMISE ; DEPRESSION

OBJECTIVE: People often report positive psychological changes after adversity, a phenomenon known as posttraumatic growth (PTG). Few PTG-focused interventions have been rigorously tested, and measurement strategies have had significant limitations. This study evaluated the effects of a new group-format psychosocial intervention, SecondStory, aimed at facilitating PTG by helping participants make meaning of the past and plan a purposeful future.
METHOD: In a randomized controlled trial, adults (N = 112, 64% women) bereaved within 5 years were randomly assigned to SecondStory or an active control, expressive writing. The primary outcome, PTG, was measured using two contrasting methods: the Posttraumatic Growth Inventory, which asks participants retrospectively how much they believe they have changed due to struggling with adversity, and the Current-Standing Posttraumatic Growth Inventory, which tracks quantifiable change in participants' standing in PTG domains over time. Secondary outcomes included depression symptoms, posttraumatic stress symptoms, and life satisfaction. Outcomes were measured at 2-week intervals: pretest, posttest, and three follow-up occasions. Hierarchical linear modeling was used to assess whether SecondStory participants experienced greater gains in primary and/or secondary outcomes over the 8-week trial.
RESULTS: Results indicated that SecondStory participants did not show significantly greater improvements than control participants on measures of PTG, posttraumatic stress, or life satisfaction, but they did show greater decreases in depression symptoms by the first follow-up.
CONCLUSIONS: These findings suggest that SecondStory may not facilitate PTG more effectively than existing interventions but may be promising for addressing depression. Positive interventions may productively be refined to support people experiencing trauma and loss.

Origine : PubMed

A randomized, controlled trial of the efficacy of percutaneous transesophageal gastro-tubing (PTEG) as palliative care for patients with malignant bowel obstruction - the JIVROSG0805 trial

ARAMAKI, Takeshi ; ARAI, Yasuaki ; TAKEUCHI, Yoshito ; SONE, Miyuki ; SATO, Rui ; BEKKU, Emima ; MORIGUCHI, Michihisa
Supportive care in cancer, 07/09/2019, Pagination inconnue

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Methotrimeprazine versus haloperidol in palliative care patients with cancer-related nausea - a randomised, double-blind controlled trial

HARDY, Janet Rea ; SKERMAN, Helen ; PHILIP, Jennifer ; GOOD, Phillip ; CURROW, David ; MITCHELL, Geoffrey ; YATES, Patsy
BMJ Open, 12/09/2019, vol.9, n°9, p. 1-9

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Expanding access to home-based palliative care - a randomized controlled trial protocol

ENGUIDANOS, Susan ; RAHMAN, Anna ; FIELDS, Torrie ; MACK, Wendy ; BRUMLEY, Richard ; RABOW, Michael ; MERT, Melissa
JOURNAL OF PALLIATIVE MEDICINE, 09/2019, vol.22, n°S1, p. 58-65

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Thème : Santé. Cote : e00.07JOU

ACCES SOIN ; ESSAI CONTROLE RANDOMISE ; HOSPITALISATION DOMICILE SOINS PALLIATIFS ; MODELE

Introduction: Studies show that home-based palliative care (HBPC) improves participant outcomes and satisfaction with care while also decreasing hospitalizations and emergency department visits. U.S. health care payment reforms create financial opportunities to offer HBPC. Consequently, more HBPC programs are emerging, heightening the need to evaluate their effectiveness.
Methods: This randomized, controlled trial is comparing the effectiveness of an evidence-based model of HBPC and enhanced usual primary care for participants who receive primary care from medical groups and clinics organized under an accountable care organization or Medicare Advantage plan. Palliative care services are reimbursed by our partnering health plan provider. The five-year trial will enroll 1155 seriously ill participants (and ~884 of their caregivers) with heart failure, chronic obstructive pulmonary disease, or advanced cancer. We are collecting data via telephone surveys with participants at baseline and one and two months postenrollment and with caregivers at baseline, one and two months postenrollments, and following the death of a loved one. We are collecting participant-reported outcome measures of pain, symptoms, anxiety, depression, participant-provider communication, and hope. Caregiver outcome measures include caregiver burden, communication with providers, anxiety, and depression. Additional outcomes are participant survival time and participants' emergency department visits and hospitalizations.
Study Implementation: Challenges and Contributions: Our research team has encountered several significant challenges in early study implementation. These include engaging primary care providers in the study and coordinating logistics with a health plan. Both challenges have contributed to a lag in participant enrollment. Despite these challenges, our study holds tremendous promise to accelerate adoption and spread of an evidence-based HBPC model across the country.

Origine : PubMed

Introducing palliative care within the treatment of end-stage liver disease - the study protocol of a cluster randomized controlled trial

VERMA, Manisha ; KOSINSKI, Andrzej S. ; VOLK, Michael L. ; TADDEI, Tamar ; RAMCHANDRAN, Kavitha ; BAKITAS, Marie ; GREEN, Kenneth ; GREEN, Lisa ; NAVARRO, Victor
JOURNAL OF PALLIATIVE MEDICINE, 09/2019, vol.22, n°S1, p. 34-43

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A multicenter, randomized controlled trial of perioperative palliative care surrounding cancer surgery for patients and their family members (PERIOP-PC)

ASLAKSON, Rebecca A. ; CHANDRASHEKARAN, Shivani V. ; RICKERSON, Elizabeth ; FAHY, Bridget N. ; JOHNSTON, Fabian M. ; MILLER, Judith A. ; CONCA-CHENG, Alison ; WANG, Suwei ; MORRIS, Arden M. ; LORENZ, Karl A. ; TEMEL, Jennifer S. ; SMITH, Thomas J.
JOURNAL OF PALLIATIVE MEDICINE, 09/2019, vol.22, n°S1, p. 44-57

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Thème : Médecine. Cote : e00.07JOU

ESSAI CONTROLE RANDOMISE ; DEMARCHE PALLIATIVE ; CANCER DIGESTIF ; CHIRURGIE

Background: Despite positive outcomes associated with specialist palliative care (PC) in diverse medical populations, little research has investigated specialist PC in surgical ones. Although cancer surgery is predominantly safe, operations can be extensive and unpredictable perioperative morbidity and mortality persist, particularly for patients with upper gastrointestinal (GI) cancers.
Objectives and Hypotheses: Our objective is to complete a multicenter, randomized controlled trial comparing surgeon-PC co-management with surgeon-alone management among patients pursuing curative-intent surgery for upper GI cancers. We hypothesize that perioperative PC will improve patient postsurgical quality of life. This study and design are based on >8 years of engagement and research with patients, family members, and clinicians surrounding major cancer surgery and advance care planning/PC for surgical patients.
Methods: Randomized controlled superiority trial with two study arms (surgeon-PC team co-management and surgeon-alone management) and five data collection points over six months. The principal investigator and analysts are blinded to randomization.
Setting: our, geographically diverse, academic tertiary care hospitals. Data collection began December 20, 2018 and continues to December 2020.
Participants: Patients recruited from surgical oncology clinics who are undergoing curative-intent surgery for an upper GI cancer.
Interventions: In the intervention arm, patients receive care from both their surgical team and a specialist PC team; the PC is provided before surgery, immediately after surgery, and at least monthly until three months postsurgery. Patients randomized to the usual care arm receive care from only the surgical team.
Main Outcomes and Measures: Primary outcome: patient quality of life. Secondary outcomes: patient: symptom experience, spiritual distress, prognostic awareness, health care utilization, and mortality. Caregiver: quality of life, caregiver burden, spiritual distress, and prognostic awareness. Intent-to-treat analysis will be used.

Origine : PubMed

Protocol for a cluster randomized trial comparing team-based to clinician-focused implementation of advance care planning in primary care

TOTTEN, Annette M. ; FAGNAN, Lyle J. ; DORR, David ; MICHAELS, LeAnn C. ; IZUMI, Shigeko Seiko ; COMBE, Angela ; LEGARE, France
JOURNAL OF PALLIATIVE MEDICINE, 09/2019, vol.22, n°S1, p. 82-89

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A systematic review and meta-analysis of randomized controlled trials of palliative care for pain among Chinese adults with cancer

ZHAO, Xin-Xin ; CUI, Meng ; GENG, Yi-Hang ; YANG, Yi-Long
BMC palliative care, 08/08/2019, vol.18, n°1, p. 1-10

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Exploratory analyses of the Danish palliative care trial (DanPaCT) - a randomized trial of early specialized palliative care plus standard care versus standard care in advanced cancer patients

JOHNSEN, Anna Thit ; PETERSEN, Morten Aagaard ; SJOGREN, Per ; PEDERSEN, Lise ; NEERGAARD, Mette Asbjoern ; DAMKIER, Anette ; GLUUD, Christian ; FAYERS, Peter M. ; LINDSCHOU, Jane ; STROMGREN, Annette S. ; NIELSEN, Jan Bjoern ; HIGGINSON, Irene J. ; GROENVOLD, Mogens
Supportive care in cancer, 13/08/2019, p. 1-11

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Efficacy of a decision aid consisting of a video and booklet on advance care planning for advanced cancer patients - randomized controlled trial

YUN, Young Ho ; KANG, EunKyo ; PARK, Sohee ; KOH, Su-Jin ; OH, Ho-Suk ; KEAM, Bhumsuk ; DO, Young Rok ; CHANG, Won Jin ; JEONG, Hyun Sik ; NAM, Eun Mi ; JUNG, Kyung Hae ; KIM, Hak Ro ; CHOO, Jiyeon ; LEE, Jihye ; SIM, Jin-Ah
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 20/08/2019, Pagination inconnue

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Teaching palliative care to health professional students - a systematic review and meta-analysis of randomized controlled trials

DONNE, Jack ; ODROWAZ, Thomas ; PIKE, Sarah ; YOUL, Bonnie ; LO, Kristin
The American journal of hospice and palliative care, 11/2019, vol.36, n°11, p. 1026-1041

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