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Physical examination of the dying patient #392

SCHNEIDERMAN, Henry ; MARKS, Sean
JOURNAL OF PALLIATIVE MEDICINE, 05/2020, vol.23, n°5, p. 721-722

Clinical evaluation of plasma coagulation parameters in patients with advanced-stage non-small cell lung cancer treated with palliative chemotherapy in China

ABBAS, Muhammad ; KASSIM, Said Abasse ; WANG, Zhong-Chang ; SHI, Meiqi ; HU, Yiqiao ; ZHU, Hai-Liang
International journal of clinical practice, 29/07/2020, p. 1-13

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Acute palliative care unit-initiated interventions for advanced cancer patients at the end of life - prediction of impending death based on Glasgow prognostic score

NAGASAKO, Yoshihide ; SUZUKI, Masahiro ; IRIYAMA, Tetsuji ; NAGASAWA, Yoko ; KATAYAMA, Yoshiki ; MASUDA, Kaori
Supportive care in cancer, 30/07/2020, Pagination inconnue

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Prediction model for death in patients with pulmonary tuberculosis accompanied by respiratory failure in ICU - retrospective study

LIU, Qiuyue ; GAO, Jingtao ; LUO, Baojian ; LIU, Junting ; ZHANG, Lin ; KANG, Wanli ; HAN, Fen
Annals of palliative medicine, 30/07/2020, p. 1-10

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Illness understanding, prognostic awareness, and end-of-life care in patients with GI cancer and malignant bowel obstruction with drainage percutaneous endoscopic gastrostomy

GOLDBERG, Jessica I. ; GOLDMAN, Debra A. ; MCCASKEY, Sarah ; KOO, Douglas J. ; EPSTEIN, Andrew S.
JCO oncology practice, 06/08/2020, Pagination inconnue

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Chemotherapy at the end of life

URVAY, Semiha ; CIVELEK, Burak ; ÖZASLAN, Ersin ; SÜREL, Aziz Ahmet
JOURNAL OF PALLIATIVE CARE, 06/08/2020, Pagination inconnue

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Understanding hospice patients' beliefs about their life expectancy - a qualitative interview study

TABER, Jennifer M. ; STACEY, Clare L. ; SHEEHAN, Denice K.
The American journal of hospice and palliative care, 10/08/2020, Pagination inconnue

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The effect of disclosing life expectancy information on patients' prognostic understanding - secondary outcomes from a multicenter randomized trial of a palliative chemotherapy educational intervention

ENZINGER, Andrea ; UNO, Hajime ; MCCLEARY, Nadine ; FRANK, Elizabeth ; SANOFF, Hanna ; VAN LOON, Katherine ; MATIN, Khalid ; BULLOCK, Andrea ; CRONIN, Christine ; BAGLEY, Janet ; SCHRAG, Deborah
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 07/08/2020, p. 1-14

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Family caregivers' emotional preparedness for death is distinct from their cognitive prognostic awareness for cancer patients

TANG, Siew Tzuh ; CHANG, Wen-Cheng ; CHOU, Wen-Chi ; HSIEH, Chia-Hsun ; CHEN, Jen-Shi ; WEN, Fur-Hsing
JOURNAL OF PALLIATIVE MEDICINE, 13/08/2020, Pagination inconnue

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Combined systemic inflammation score (SIS) correlates with prognosis in patients with advanced pancreatic cancer receiving palliative chemotherapy

MARKUS, M. ; ABENDROTH, A. ; NOUREDDINE, R. ; PAUL, A. ; BREITENBUECHER, S. ; VIRCHOW, I. ; SCHMID, K. W. ; MARKUS, P. ; SCHUMACHER, B. ; WIESWEG, M. ; WENDLING, J. ; MENDE, B. ; SIVEKE, J. T. ; SCHULER, M. ; KASPER, S.
Journal of cancer research and clinical oncology, 25/08/2020, p. 1-13

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Thème : Médecine. Cote : eD03.01.01

ETUDE RETROSPECTIVE ; SYMPTOME ; CANCER DIGESTIF ; PRONOSTIC

Purpose: The prognosis of patients with advanced pancreatic ductal adenocarcinoma (PDAC) remains dismal. New cytotoxic agents such as nab-paclitaxel and liposomal irinotecan (nal-Iri) have extended the armamentarium of therapeutic options in the last years. Nowadays, sequential therapeutic strategies with moderately toxic chemotherapeutic protocols can be administered to the patients. However, prognostic and predictive biomarkers are still missing to identify those patients, which profit most from a “continuum of care” concept rather than receiving intensive first-line protocols such as FOLFIRINOX. To this end, we retrospectively evaluated the impact of the systemic inflammation as one essential hallmark of cancer in patients with advanced PDAC treated with sequential systemic.
Methods: A cohort of 193 PDAC patients treated at our center from January 2005 to August 2011 were retrospectively evaluated for the following systemic inflammatory response (SIR) markers: neutrophil–lymphocyte ratio (NLR), lymphocyte–monocyte ratio (LMR) C-reactive protein (CRP), and the modified Glasgow Prognostic Score (mGPS). SIR markers were correlated with clinico-pathological findings, response to chemotherapy and overall survival (OS) using Kaplan–Meier curves and Cox proportional models.
Results: All evaluated SIR markers were significantly associated with OS in patients with metastatic disease but not in patients with locally advanced PDAC. Interestingly, all SIR markers were only prognostic in patients not receiving antibiotics as surrogate marker for systemic bacterial infections. Based on the evaluated SIR markers, we propose a new Systemic Inflammation Score (SIS), which significantly correlated with reduced OS (HR: 3.418 (1.802–6.488, p < 0.001)) and the likelihood of receiving further-line systemic therapies (p = 0.028).
Conclusion: Routinely assessed SIR biomarkers have potential to support therapeutic decision making in patients with metastatic PDAC.

Origine : PubMed

Variations in vital signs at the end of life in non-cancer patients - a retrospective study

HOSOI, Takahiro ; OZONE, Sachiko ; HAMANO, Jun
Annals of palliative medicine, 19/08/2020, p. 1-6

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Baseline Karnofsky performance status is independently predictive of death within 30 days of intracranial radiation therapy completion for metastatic disease

MCCLELLAND III, Shearwood ; AGRAWAL, Namita ; ELBANNA, May F. ; SHIUE, Kevin ; BARTLETT, Gregory K. ; LAUTENSCHLAEGER, Tim ; ZELLARS, Richard C. ; WATSON, Gordon A. ; ELLSWORTH, Susannah G.
Reports of practical oncology and radiotherapy, 08/2020, vol.25, n°4, p. 698-700

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The palliative performance scale predicts mortality in hospitalized patients with Covid-19

FIORENTINO, Michele ; PENTAKOTA, Sri Ram ; MOSENTHAL, Anne C. ; GLASS, Nina E.
PALLIATIVE MEDICINE, 17/07/2020, Pagination inconnue

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Palliative lung radiotherapy - higher dose leads to improved survival?

LEWIS, T. S. ; KENNEDY, J. A. ; PRICE, G. J. ; MEE, T. ; WOOLF, D. K. ; BAYMAN, N. A. ; CHAN, C. ; COOTE, J. H. ; FAIVRE-FINN, C. ; HARRIS, M. A. ; HUDSON, A. M. ; PEMBERTON, L. S. ; SALEM, A. ; SHEIKH, H. Y. ; MISTRY, H. B. ; COBBEN, D. C. P.
Clinical oncology, 26/06/2020, p. 1-11

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Physician-predicted prognosis and palliative radiotherapy treatment utilization at the end-of-life - an audit of a large cancer center network

MOJICA-MARQUEZ, Adrianna E. ; RODRIGUEZ-LOPEZ, Joshua L. ; PATEL, Ankur K. ; LING, Diane C. ; RAJAGOPALAN, Malolan S. ; BERIWAL, Sushil
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 26/06/2020, p. 1-53

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Systematic symptom and problem assessment at admission to the palliative care ward - perspectives and prognostic impacts

COYM, Anja ; ULLRICH, Anneke ; HACKSPIEL, Lisa Kathrin ; AHRENHOLZ, Mareike ; BOKEMEYER, Carsten ; OECHSLE, Karin
BMC palliative care, 28/05/2020, vol.19, n°1, p. 1-11

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Deaths in dementia - a scoping review of prognostic variables

KAUR, Palvinder ; TAN, Woan Shin ; GUNAPAL, Pradeep Paul George ; DING, Yew Yoong ; ONG, Reuben ; WU, Huei Yaw ; HUM, Allyn
BMJ supportive and palliative care, 19/06/2020, Pagination inconnue

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The 6-star doctor? - physicians’ communication of poor prognosis to patients and their families in Cape Coast, Ghana

CAULFIELD, Alexandra ; PLYMOTH, Amelie ; NARTEY, Yvonne Ayerki ; MOLSTED-ALVESSON, Helle
BMJ global health, 06/2020, vol.5, n°6, p. 1-10

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30-day mortality following palliative radiotherapy

KAIN, Mollie ; BENNETT, Hayley ; YI, Ma ; ROBINSON, Bridget ; JAMES, Melissa
Journal of medical imaging and radiation oncology, 27/06/2020, Pagination inconnue

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External validation of life expectancy prognostic models in patients evaluated for palliative radiotherapy at the end-of-life

MOJICA-MARQUEZ, Adrianna E. ; RODRIGUEZ-LOPEZ, Joshua L. ; PATEL, Ankur K. ; LING, Diane C. ; RAJAGOPALAN, Malolan S. ; BERIWAL, Sushil
Cancer medicine, 26/06/2020, p. 1-7

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