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Stability and impact of symptom clusters in patients with end-stage renal disease undergoing dialysis

NAM, Marques Shek ; KWOK SO, Winnie ; WONG, Cho Lee ; HUI, Yun Ho ; HAU SIM HO, Eva ; CHOI, Kai Chow ; COOPER, Bruce ; MIASKOWSKI, Christine
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 01/2020, vol.59, n°1, p. 67-76

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Covid-19 crisis triage - optimizing health outcomes and disability rights

SOLOMON, Mildred Z. ; WYNIA, Matthew K. ; GOSTIN, Lawrence O.
The New England journal of medicine, 19/05/2020, p. 1-3

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Measuring quality of life in life-threatening illness - content validity and response processes of MQOL-E and QOLLTI-F in Swedish patients and family carers

AXELSSON, Lena ; ALVARIZA, Anette ; CARLSSON, Nina ; COHEN, S. Robin ; SAWATZKY, Richard ; ARESTEDT, Kristofer
BMC palliative care, 12/2020, vol.19, n°1, p. 1-9

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Effects of a telehealth early palliative care intervention for family caregivers of persons with advanced heart failure - the ENABLE CHF-PC randomized clinical trial

DIONNE-ODOM, J. Nicholas ; EJEM, Deborah B. ; WELLS, Rachel ; AZUERO, Andres ; STOCKDILL, Macy L. ; KEEBLER, Konda ; SOCKWELL, Elizabeth ; TIMS, Sheri ; ENGLER, Sally ; KVALE, Elizabeth ; DURANT, Raegan W. ; TUCKER, Rodney O. ; BURGIO, Kathryn L. ; TALLAJ, Jose ; PAMBOUKIAN, Salpy V. ; SWETZ, Keith M. ; BAKITAS, Marie A.
JAMA network open, 13/04/2020, vol.3, n°4, Pagination inconnue

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Seriously ill patients’ willingness to trade survival time to avoid high treatment intensity at the end of life

RUBIN, Emily B. ; BUEHLER, Anna ; HALPERN, Scott D.
JAMA internal medicine, 06/04/2020, Pagination inconnue

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Determinants of quality of life in patients with incurable cancer - quality of life in incurable cancer

DALY, Louise E. ; DOLAN, Ross D. ; POWER, Derek G. ; NI BHUACHALLA, Éadaoin ; SIM, Wei ; CUSHEN, Samantha J. ; FALLON, Marie T. ; SIMMONS, Claribel ; MCMILLAN, Donald C. ; LAIRD, Barry J. ; RYAN, Aoife M.
Cancer, 08/04/2020, Pagination inconnue

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Thème : Soins.

CANCER ; QUALITE VIE ; FACTEUR ; IRLANDE ; ROYAUME UNI

Background: Optimizing quality of life (QoL) remains the central tenet of care in patients with incurable cancer; however, determinants of QoL are not clear. The objective of the current study was to examine which factors influence QoL in patients with incurable cancer.
Methods: A multicenter study of adult patients with advanced cancer was conducted in Ireland and the United Kingdom between 2011 and 2016. Data were collected from patients at study entry and included patient demographics, Eastern Cooperative Oncology Group performance status (ECOG-PS), nutritional parameters (the percentage weight loss [%WL]), muscle parameters assessed using computed tomography images (skeletal muscle index and skeletal muscle attenuation), inflammatory markers (modified Glasgow Prognostic score [mGPS]), and QoL data (the European Organization for Research and Treatment Quality-of-Life Questionnaire C-30). The relation between clinical, nutritional, and inflammatory parameters with QoL was assessed using the Spearman rank correlation coefficient and multivariate binary logistic regression. Components of the European Organization for Research and Treatment Quality-of-Life Questionnaire C-30 (physical function, fatigue, and appetite loss) and summary QoL scores were mean-dichotomized for the logistic regression analyses.
Results: Data were available for 1027 patients (51% men; median age, 66 years). Gastrointestinal cancer was most prevalent (40%), followed by lung cancer (26%) and breast cancer (9%). Distant metastatic disease was present in 87% of patients. The %WL, ECOG-PS, and mGPS were significantly correlated with deteriorating QoL functional and symptom scales (all P < .001). On multivariate regression analysis, >10% WL (odds ratio [OR], 2.69; 95% CI, 1.63-4.42), an ECOG-PS of 3 or 4 (OR, 14.33; 95% CI, 6.76-30.37), and an mGPS of 2 (OR, 1.58; 95% CI, 1.09-2.29) were independently associated with poorer summary QoL scores. These parameters were also independently associated with poorer physical function, fatigue, and appetite loss (all P < .05). Low skeletal muscle attenuation was independently associated with poorer physical functioning (OR, 1.67; 95% CI, 1.09-2.56), but muscle parameters were not independently associated with fatigue, appetite loss, or QoL summary scores.
Conclusions: The current findings indicate that QoL is determined (at least in part) by WL, ECOG-PS, and the systemic inflammatory response in patients with advanced cancer. Identifying early predictors of poor QoL may allow the identification of patients who may benefit from early referral to palliative and supportive care, which has been shown to improve QoL.

Origine : DOI.org (Crossref

Sex differences in quality of life and clinical outcomes in patients with advanced heart failure - insights from the PAL-HF trial

TRUBY, Lauren K. ; O’CONNOR, Christopher ; FIUZAT, Mona ; STEBBINS, Amanda ; COLES, Adrian ; PATEL, Chetan B. ; GRANGER, Bradi ; PAGIDIPATI, Neha ; AGARWAL, Richa ; RYMER, Jennifer ; LOWENSTERN, Angela ; DOUGLAS, Pamela S. ; TULSKY, James A. ; ROGERS, Joseph G. ; MENTZ, Robert J.
CIRCULATION, 04/2020, vol.13, n°4, Pagination inconnue

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Thème : Soins.

GENRE ; QUALITE VIE ; INSUFFISANCE CARDIAQUE ; DEMARCHE PALLIATIVE

Background: Palliative care improves quality of life in patients with heart failure. Whether men and women with heart failure derive similar benefit from palliative care interventions remains unknown.
Methods: In a secondary analysis of the PAL-HF trial (Palliative Care in Heart Failure), we analyzed differences in quality of life among men and women with heart failure and assessed for differential effects of the palliative care intervention by sex. Differences in clinical characteristics and quality-of-life metrics were compared between men and women at serial time points. The primary outcome was change in Kansas City Cardiomyopathy Questionnaire score between baseline and 24 weeks.
Results: Among the 71 women and 79 men, there was a significant difference in baseline Kansas City Cardiomyopathy Questionnaire (24.5 versus 36.2, respectively; P=0.04) but not Functional Assessment of Chronic Illness Therapy-Palliative Care scale (115.7 versus 120.3; P=0.27) scores. Among those who received the palliative care intervention (33 women and 42 men), women’s quality-of-life score remained lower than that of men after enrollment. Treated men’s scores were significantly higher than those untreated (6-month Kansas City Cardiomyopathy Questionnaire, 68.0 [interquartile range, 52.6–85.7] versus 41.1[interquartile range, 32.0–78.3]; P=0.047), whereas the difference between treated and untreated women was not significantly different (P=0.39). Rates of death and rehospitalization, as well as the composite end point, were similar between treated and untreated women and men.
Conclusions: In the PAL-HF trial, women with heart failure experienced a greater symptom burden and poorer quality of life as compared with men. The change in treated men’s Kansas City Cardiomyopathy Questionnaire score between baseline and 24 weeks was significantly higher than those untreated; this trend was not observed in women. Thus, there may be a sex disparity in response to palliative care intervention, suggesting that sex-specific approaches to palliative care may be needed to improve outcomes.

Origine : DOI.org (Crossref

Embedded palliative care for patients with metastatic colorectal cancer - a mixed-methods pilot study

BISCHOFF, Kara E. ; ZAPATA, Carly ; SEDKI, Sarah ; URSEM, Carling ; O’RIORDAN, David L. ; ENGLAND, Ashley Eaton ; THOMPSON, Nicole ; ALFARO, Ariceli ; RABOW, Michael W. ; ATREYA, Chloe E.
Supportive care in cancer, 14/04/2020, Pagination inconnue

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Correlation between ways of coping and quality of life in Iranian husbands of women with breast cancer

BIGDELI SHAMLOO, Marzieh Beigom ; NASIRI, Morteza ; MANEIY, Mohammad ; KIARSI, Maryam ; MADMOLI, Yaghoub
International Journal of Palliative Nursing, 02/2020, vol.26, n°2, p. 84-90

Counting the cost of denying assisted dying

SHAW, David ; MORTON, Alec
Clinical ethics, 10/03/2020, Pagination inconnue

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We all want to die in peace - so why don't we?

GIJSBERTSEN, Brecht ; KREMER, Jan A. M.
BMJ supportive and palliative care, 13/03/2020, Pagination inconnue

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The impact of palliative care on clinical and patient-centred outcomes in patients with advanced heart failure - a systematic review of randomized controlled trials

SAHLOLLBEY, Nick ; LEE, Christopher Kai Seng ; SHIRIN, Afraah ; JOSEPH, Philip
European journal of heart failure, 16/03/2020, Pagination inconnue

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Patient-reported symptoms and problems at admission to specialized palliative care improved survival prediction in 30,969 cancer patients - a nationwide register-based study

HANSEN, Maiken B. ; NYLANDSTED, Lone Ross ; PETERSEN, Morten A. ; ADSERSEN, Mathilde ; ROJAS-CONCHA, Leslye ; GROENVOLD, Mogens
PALLIATIVE MEDICINE, 18/03/2020, Pagination inconnue

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Early palliative care and quality of life of advanced cancer patients - a multicenter randomized clinical trial

FRANCIOSI, Vittorio ; MAGLIETTA, Giuseppe ; DEGLI ESPOSTI, Claudia ; CARUSO, Giuseppe ; CAVANNA, Luigi ; BERTE, Raffaella ; BACCHINI, Gianpaolo ; BOCCHI, Letizia ; PIVA, Erico ; MONFREDO, Michela ; SCAFURI, Valentina ; DI CESARE, Pamela ; MELOTTI, Barbara ; SEQUINO, Manuel ; RIMANTI, Anita ; BINOVI, Cinzia ; GHISONI, Francesco ; CAMINITI, Caterina
Annals of palliative medicine, 09/2019, vol.8, n°4, p. 381-389

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Advance care planning for adults with heart failure

NISHIKAWA, Yuri ; HIROYAMA, Natsuko ; FUKAHORI, Hiroki ; OTA, Erika ; MIZUNO, Atsushi ; MIYASHITA, Mitsunori ; YONEOKA, Daisuke ; KWONG, Joey Sw
The Cochrane database of systematic reviews, 27/02/2020, vol.2, p. 1-73

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Describing the psychosocial profile and unmet support needs of parents caring for a child with a life-limiting condition - a cross-sectional study of caregiver-reported outcomes

COLLINS, Anna ; BURCHELL, Jodie ; REMEDIOS, Cheryl ; THOMAS, Kristina
PALLIATIVE MEDICINE, 27/02/2020, Pagination inconnue

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CRESPO, Iris ; RODRIGUEZ-PRAT, Andrea ; MONFORTE-ROYO, Cristina ; WILSON, Keith G. ; PORTA-SALES, Josep ; BALAGUER, Albert
PALLIATIVE MEDICINE, 27/02/2020, Pagination inconnue

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Assessment of quality of life among end-stage renal disease patients undergoing maintenance hemodialysis

RAVINDRAN, Ashima ; SUNNY, Anjali ; KUNNATH, Rajesh Penganazhi ; DIVAKARAN, Binoo
Indian journal of palliative care, 03/2020, vol.26, n°1, p. 47-53

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Evaluating the feasibility and acceptability of the Namaste care program in long-term care settings in Canada

KAASALAINEN, Sharon ; HUNTER, Paulette V. ; DAL BELLO-HAAS, Vanina ; DOLOVICH, Lisa ; FROGGATT, Katherine ; HADJISTAVROPOULOS, Thomas ; MARKLE-REID, Maureen ; PLOEG, Jenny ; SIMARD, Joyce ; THABANE, Lehana ; VAN DER STEEN, Jenny T. ; VOLICER, Ladislav
Pilot and feasibility studies, 2020, vol.6, p. 1-12

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