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RADIOTHERAPIE

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Paravertebral muscle training in patients with unstable spinal metastases receiving palliative radiotherapy - an exploratory randomized feasibility trial

SPRAVE, Tanja ; ROSENBERGER, Friederike ; VERMA, Vivek ; FÖRSTER, Robert ; BRUCKNER, Thomas ; SCHLAMPP, Ingmar ; BOSTEL, Tilman ; WELZEL, Thomas ; AKBABA, Sati ; RACKWITZ, Tilman ; NICOLAY, Nils Henrik ; GROSU, Anca-Ligia ; WISKEMANN, Joachim ; DEBUS, Jürgen ; RIEF, Harald
Cancers, 11/11/2019, vol.11, n°11, p. 1-15

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An evaluation of an advanced practice role in palliative radiation therapy

JOB, Mary ; HOLT, Tanya ; BERNARD, Anne
Journal of medical radiation sciences, 06/2019, vol.66, n°2, p. 96-102

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Palliative radiotherapy - inpatients, outpatients, and the changing role of supportive care in radiation oncology

ARSCOTT, William Tristram ; EMMETT, Jaclyn ; GHIAM, Alireza Fotouhi ; JONES, Joshua A.
Hematology/Oncology Clinics of North America, 02/2020, vol.34, n°1, p. 253-277

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SUPR-3D - a randomized phase iii trial comparing simple unplanned palliative radiotherapy versus 3d conformal radiotherapy for patients with bone metastases: study protocol

OLSON, Robert ; SCHLIJPER, Roel ; CHNG, Nick ; MATTHEWS, Quinn ; ARIMARE, Marco ; MATHEWS, Lindsay ; HSU, Fred ; BERRANG, Tanya ; LOUIE, Alexander ; MOU, Benjamin ; VALEV, Boris ; LABA, Joanna ; PALMA, David ; SCHELLENBERG, Devin ; LEFRESNE, Shilo
BMC Cancer, 28/10/2019, vol.19, n°1, p. 1-8

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Efficacy of palliative bladder radiotherapy for hematuria in advanced bladder cancer using contemporary radiotherapy techniques

TEY, Jeremy ; SOON, Yu Yang ; CHEO, Timothy ; OOI, Kiat Huat ; HO, Francis ; VELLAYAPPAN, Balamurugan ; CHIA, David ; TAI, Bee Choo
In Vivo, 12/2019, vol.33, n°6, p. 2161-2167

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Clinical specialist radiation therapist in palliative radiation therapy - report of an orientation, training, and support program

LINDEN, Kelly ; RENAUD, Julie ; ZOHR, Robert ; GAUDET, Marc ; HADDAD, Alain ; PANTAROTTO, Jason ; DENNIS, Kristopher
Journal of medical imaging and radiation sciences, 24/10/2019, Pagination inconnue

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Thème : Soins.

RADIOTHERAPIE ; FORMATION ; MEDECIN ; ROLE

INTRODUCTION: A clinical specialist radiation therapist (CSRT) position in palliative radiation therapy (RT) was created at our institution. Herein, we report the details of the CSRT's orientation, training, and support program.
METHODS: We performed an audit and needs assessment of palliative RT services at our centre. This identified opportunities for improvement that could be facilitated by the CSRT. We defined the CSRT job description including priority responsibilities: (1) optimizing palliative RT services for outpatients and developing a rapid access palliative RT program, (2) optimizing palliative RT services for inpatients at our institution, (3) improving links to community physicians and hospitals caring for patients with advanced cancers. We formed a core resource team to provide ongoing support and to design and implement the orientation and training program. The program involved training in clerical and administrative systems as well as treatment planning and physics training relevant to palliative RT. Clinical placements at several hospitals were arranged in both inpatient and outpatient settings. The CSRT worked with radiation and medical oncologists, palliative care specialists, nurse practitioners, hospitalists, and social workers.
RESULTS: Through clinical placements and self-directed learning, the CSRT gained knowledge and competencies in patient care coordination, history taking and physical examination, clinical oncology practice including the evidence-based use of palliative RT and symptom control measures, treatment planning, communication, patient advocacy, and advance care planning. We provided practice resources including office space and a planning station, educational opportunities including workshops in palliative and psychosocial care, and research opportunities including methodologic and research ethics training.
DISCUSSION: To our knowledge, this is the first detailed report of its kind for an advanced practice radiation therapy role. We hope our report will inform the design and implementation of programs elsewhere to help prepare individuals for similar roles in palliative RT.
CONCLUSION: The CSRT in palliative RT at our institution underwent a comprehensive orientation and training program. Institutions with similar CSRT positions are encouraged to report the details of their own programs.

Origine : PubMed

Current landscape of palliative radiotherapy for non-small-cell lung cancer

JUMEAU, Raphael ; VILOTTE, Florent ; DURHAM, André-Dante ; OZSAHIN, Esat-Mahmut
Translational lung cancer research, 09/2019, vol.8, n°Suppl 2, p. S192-S201

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The role of palliative interventional radiotherapy (brachytherapy) in esophageal cancer - an AIRO (Italian Association of Radiotherapy and Clinical Oncology) systematic review focused on dysphagia-free survival

LANCELLOTTA, Valentina ; CELLINI, Francesco ; FIONDA, Bruno ; DE SANCTIS, Vitaliana ; VIDALI, Cristiana ; FUSCO, Vincenzo ; BARBERA, Fernando ; GAMBACORTA, Maria Antonietta ; CORVO, Renzo ; MAGRINI, Stefano Maria ; TAGLIAFERRI, Luca
Brachytherapy, 18/10/2019, Pagination inconnue

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Short-course 2d-radiotherapy in the palliative treatment of oesophageal cancer in a developing country - a phase II study (Sharon Project)

DERESSA, Biniyam Tefera ; TIGENEH, Wondemagegnehu ; BOGALE, Netsanet ; BUWENGE, Milly ; MORGANTI, Alessio G. ; FARINA, Eleonora
International journal of radiation oncology, biology, physics, 14/10/2019, Pagination inconnue

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Palliative resection or radiation of primary tumor prolonged survival for metastatic esophageal cancer

XU, Jing ; LU, Donghui ; ZHANG, Li ; LI, Jian ; SUN, Guoping
Cancer medicine, 14/10/2019, p. 1-12

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Noncurated data lead to misinterpretation of treatment outcomes in patients with prostate cancer after salvage or palliative radiotherapy

RUTZNER, Sandra ; GANSLANDT, Thomas ; FIETKAU, Rainer ; PROKOSCH, Hans-Ulrich ; LUBGAN, Dorota
JCO clinical cancer informatics, 10/2019, vol.3, p. 1-11

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Thème : Médecine.

CANCER URO NEPHROLOGIQUE ; RADIOTHERAPIE ; STATISTIQUE ; THERAPEUTIQUE ANTI CANCEREUSE

PURPOSE: Clinical data warehouses (cDWHs) and cancer registry databases have enabled researchers to conduct clinical analytics with structured electronic health record data. However, these secondary electronic health record sources are often limited in scope because they do not capture the clinical information needed to understand complex clinical questions. Thus, we evaluated the effect of additional curation of data.
MATERIALS AND METHODS: Clinical data sets of 149 patients with prostate cancer with biochemical recurrence after radical prostatectomy treated with salvage or palliative radiotherapy between 2008 and 2017 from our institutional cDWH and Gießener Tumor Documentation System (GTDS) were linked (data warehouse [DWH] population) for analyzing treatment outcomes. The linked data sets were manually curated (manual postprocessing [MPP], eg, incorporate data from established urologists). The primary outcomes were the impact on data quality of treatment outcomes and the time spent on data curation.
RESULTS: We obtained significantly more information on disease progression and patient survival (nonsignificant) when using curated data; the biochemical progression-free survival rate at 5 years for the DWH and DWH plus MPP populations was 63% v 30% (P = .001) and the overall survival rate was 84% v 81% (P = .479), respectively. The median deviation of completeness and the median concordance of clinical data values were 21.47% (range, 55.38%-100%) and 95.00% (range, 63.40%-100%), respectively. We spent 121 hours, 42 minutes on data curation, with most time required for laboratory values, accounting, for a total of 45 hours, 20 minutes (37.26%).
CONCLUSION: Our analysis indicates that time-to-event outcomes for patients with prostate cancer cannot be extracted using secondary data sources (cDWH plus GTDS) only. Outcomes data differed between the electronic data (DWH) and the second manual extraction (DWH plus MPP) because of a lack of follow-up data. When using such unique database resources, only baseline characteristics can reliably be extracted.

Origine : PubMed

Palliative radiotherapy - what do nurses know?

HAYDEN, Kim ; CONNOLLY, Michael
British journal of nursing, 10/10/2019, vol.28, n°18, p. 1202-1206

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Radiotherapy for the palliation of advanced sarcomas - the effectiveness of radiotherapy in providing symptomatic improvement for advanced sarcomas in a single centre cohort

TWEEN, Hannah ; PEAKE, David ; SPOONER, David ; SHERRIFF, Jenny
Healthcare, 18/10/2019, vol.7, n°4, p. 1-9

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Thème : Médecine. Cote : eD03.05

RADIOTHERAPIE ; ETUDE COHORTE ; CANCER

Background: Sarcomas are rare and heterogeneous tumours with a large proportion of patients requiring palliative intervention. They are regarded as relatively radioresistant and therefore achieving good palliation with radiation may require larger doses than for more common solid tumour types. Limited data is available regarding appropriate palliative radiotherapy dose fractionation. This case series aims to assess the effectiveness of radiotherapy in providing symptomatic improvement for advanced sarcomas.
Method: Data was retrospectively collected for patients treated with palliative radiotherapy between July 2010 and April 2019 at one institution. The primary outcome was documented symptomatic improvement following radiotherapy. Secondary outcome was overall survival.
Results: One hundred and five patients had a total of 137 sites treated using 25 different dose fractionation schedules. The median patient age was 54 (range 8–90) years. Treated sites included 114 soft tissue and 23 bone sarcomas. Data on symptomatic improvement was available in 56% and 67% of cases respectively. A total of 70% of soft tissue and 55% of bone sarcoma patients reported symptomatic improvement. Symptomatic response rates appeared to increase to a biological effective dose (BED) of 50Grey4 (Gy4) (alpha beta ratio (a/ß) = 4 for tumour) but did not continue to improve with further rises in dose beyond this.
onclusion: Palliative radiotherapy offers symptomatic improvement for sarcoma patients with two-thirds of patients reporting reduction in symptoms. These results are limited by the heterogeneous study population including different sarcoma subtypes each with a probable different radio-sensitivity, treated with different radiotherapy schedules. Further prospective data collection is needed considering sarcoma subtype radio-sensitivity, to determine appropriate palliative dose fractionation schedules.

Origine : PubMed

Palliative chemotherapy or radiation and prognostic understanding among advanced cancer patients - the role of perceived treatment intent

GEORGE, Login S. ; PRIGERSON, Holly G. ; EPSTEIN, Andrew S. ; RICHARDS, Kristy L. ; SHEN, Megan J. ; DERRY, Heather M. ; REYNA, Valerie F. ; SHAH, Manish A. ; MACIEJEWSKI, Paul K.
JOURNAL OF PALLIATIVE MEDICINE, 08/10/2019, p. 1-7

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Palliative radiotherapy for pediatric patients - parental perceptions of indication, intent, and outcomes

LEE, Becky K. ; BOYLE, Patrick J. ; ZASLOWE-DUDE, Cierra ; WOLFE, Joanne ; MARCUS, Karen J.
Pediatric blood and cancer, 04/10/2019, Pagination inconnue

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Effective delivery of palliative radiotherapy - a prospective study

CLÉMENT-ZHAO, A. ; LUU, M. ; BIBAULT, J.-E. ; DAVEAU, C. ; KREPS, S. ; JAULMES, H. ; DESSARD-DIANA, B. ; HOUSSET, M. ; GIRAUD, P. ; DURDUX, C.
Cancer radiotherapie, 09/2019, vol.23, n°5, p. 365-369

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Variation in the use of single- versus multi-fractions palliative radiotherapy for bone metastases in Australia

ONG, Wee Loon ; FOROUDI, Farshad ; MILNE, Roger L. ; MILLAR, Jeremy L.
International journal of radiation oncology, biology, physics, 07/09/2019, p. 1-20

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Effect and toxicity of radiation therapy in selected palliative indications

PECHACOVA, Z. ; ZEMANOVA, M. ; KONCEKOVA, J.
Klinicka onkologie, 2018, vol.31, n°6, p. 439-447

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A video decision aid improves informed decision-making in patients with advanced cancer considering palliative radiation therapy

DHARMARAJAN, Kavita V. ; WALTERS, Chasity B. ; LEVIN, Tomer T. ; MILAZZO, Carol Ann ; MONETHER, Christopher ; RAWLINS-DUELL, Robin ; TICKOO, Roma ; SPRATT, Daniel E. ; LOVIE, Shona ; GIANNANTONI-IBELLI, Gina ; MCCORMICK, Beryl
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 28/08/2019, Pagination inconnue

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Time to diagnosis and treatment with palliative radiotherapy among Inuit patients with cancer from the arctic territory of Nunavut, Canada

CHAN, J. ; LINDEN, K. ; MCGRATH, C. ; RENAUD, J. ; DOERING, P. ; MAC DONALD, S. ; GAUDET, M. ; PANTAROTTO, J. R. ; ASMIS, T. ; SLOTMAN, B. ; DENNIS, K.
Clinical oncology, 19/07/2019, Pagination inconnue

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